Cows' habitual abortion is a common obstetric disease and often causes significant economic losses to cattle farmers. After several years of exploration and practice, we have proven that the use of progesterone to treat this disease has a certain effect. Early abortions generally occur during the 40-60 days of cow's pregnancy, and it is not easy to have abortions. Therefore, pregnant cows with a history of habitual abortion must be prevented and treated in advance during this period. Pharmacological Analysis Progesterone is the most important progesterone. Its main source is the secretion of luteal cells in the ovary. Its main function is to thicken the uterine mucosa, promote the growth and development of the glands in the mucosa, and enhance the secretory function of the uterus. It is beneficial to the colonization of blastocysts. Promote the contraction of the uterine cervix, mucous thickening of the uterus, to prevent foreign invasion, is conducive to miscarriage. Pathological analysis The fertilized egg runs from the fallopian tube to the uterus, which is controlled by the gradual decrease in the level of estrogen after estrus and the increase in the number of progesterone. If the two are not balanced, the uterine environment will be disturbed and the operation of the fertilized egg will be accelerated or slowed down, which will result in failure of the colonization and even cause the death of the fetus. The main cause of the imbalance between estrogen and progesterone is the degeneration of the corpus luteum in the body and the lack of progesterone secretion. Therefore, the reduction of progesterone is the main cause of habitual early abortion. Prevention and treatment methods We selected 20 cows with habitual early miscarriage. On the second day of artificial insemination, 5 intramuscular injections of progesterone per head were used. Each 2 ml (20 mg) was intramuscularly injected on the 5th day. Head progesterone, observed in one production cycle, was produced successfully without any miscarriage, and the rate of miscarriage was 100%. Summary The use of progesterone to prevent early abortion of dairy cows is simple, effective, easy to promote, and can avoid or reduce the economic losses of cattle farmers. Practice has proved that while conducting drug control, we must also pay attention to strengthening the feeding and management of pregnant cows to avoid artificial and mechanical abortion.
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