Application of cell culture equipment in CAR-T cell immunotherapy technology

CAR-T Cell Immunotherapy Technology Since October 2017, the US government has approved a second treatment based on the modification of patients' autoimmune cells, which has been effective in treating cancer.
The full name of CAR-T treatment is Chimeric Antigen Receptor T-Cell Immunotherapy, which refers to chimeric antigen receptor T cell immunotherapy, which has significant efficacy in the treatment of acute leukemia and non-Hodgkin's lymphoma. It is considered to be the most One of the prospects for cancer treatment.
CAR-T technology has been around for many years. The basic principle is to use the patient's own immune cells
to clear cancer cells, but the difference is that this is a cell therapy, not a drug.

The mechanism of CAR-T treatment is briefly introduced.
There are a series of cells in the human body that constitute the immune system in the human body, including B cells that produce antibodies, macrophages that phagocytose foreign bodies, and T cells that directly kill harmful or harmful cells. T cells, also called T lymphocytes. . T cells patrol the human body like a guardian guard, encountering viruses that are harmful to human health, and cells will be eliminated and eliminated.

Cancer cells have a good camouflage ability to camouflage adult normal cells. T cells will consider these cancer cells to be healthy cells of the body and not align them.


Scientists take a certain number of T cells from the patient and modify the antigen receptors of the T cells. The modified T cells can recognize specific cancer cells. Scientists have expanded the cultured T cells in vitro by instrumentation. The modified T cells are cultured in large quantities and injected into the patient.
The modified and expanded T cells injected into the patient are equivalent to providing the body with a T cell army that recognizes and kills the cancer cells. These intensive T-cell guards patrol the body, and the camouflage of cancer cells loses their effect in the face of these strengthened T cells. T cells kill and remove cancer cells just like killing common invading foreign bodies, thus curing cancer.

INFORS special cell culture shaker, cell bioreactor, WIGGENS carbon dioxide shaking incubator, widely used in the field of CAR-T cell immunotherapy. In the industry, we have received high evaluation from our customers and made due contributions to the medical and health field.


INFORS cell culture special shaker

WIGGENS CO2 Oscillating Incubator

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