The global gene chip market is gradually opening up, and the HSMAP gene chip in-depth report has also been fully attacked. The report will comprehensively analyze genes from the commercial road, development history, technical route, research heat, clinical application, industrial progress and typical companies. The mystery of the chip!
The information and data in this article are from hsmap (Flint Map)!
Open the commercial road of gene chips
In the 1980s, Edwin Southern of Oxford University and Stephen Fodor of the Affymax Institute of Palo Alto, California, carried out an exciting and promising work in their respective laboratories – the development of gene chips.
Southern invented a printing technique that prints bases onto a glass substrate to form an oligonucleotide sequence. At the same time, Fodor uses photolithography to etch tiny patterns on the semiconductor chip.
In 1991, Fodor's research work was published on the cover of Science magazine.
Subsequently, Fodor founded Affymetrix, and Southern founded Oxford Gene Technology, which commercialized the two technologies and opened the commercial path of gene chips.
The development of gene chips
We are moving into the functional genomic era from the era of structural genomics. It is not enough to know the primary structure of biological genome sequences. It is also necessary to understand the formation of gene structure and the function of each gene. Gene chip technology is a relatively effective research tool in the study of functional genomics.
This section will cover the milestones experienced by the development of gene chips from germination to growth.
Gene chip technology route
This section will sort out the technical route of gene chips, including the types of gene chips, preparation methods, detection methods and data processing methods.
Gene chip research fever
At present, the concept of " precise medical care " has swept the world. Gene chip as a molecular diagnostic tool in precision medicine , research heat is continuing to heat up. This section will interpret the hotspots and research hotspots of global research from the two dimensions of scientific papers and patents.
Clinical application of gene chip
The clinical application of gene chips has been gradually liberalized. The number of marketable gene chip products approved by CFDA in the past five years is four times that of the previous approval, and the application scope covers viral genotyping, drug resistance mutation detection, genetics and tumors. Genetic testing and other aspects.
This section will introduce the three major clinical applications of gene chips and typical clinical research methods.
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