Lab Polypeptide Hormone Peptide Follistatin Fst 344

Model NO.: WSPEPHS07
Name: Follistatin 344
Other Name: Follistatin 315, Ace 031
Assay: 99%
Water: 5.43%
Acetic Acid: 6.45%
Trifluoroacetic Acid: 0.08%
Peptide: 88.45%
Payment: Wu, Mg, Tt, Paypal, Wechat
Delivery: 7-15days
Brand: Wide
Trademark: Wide, Follistatin 344
Transport Package: Packed in Glass Bottles
Specification: 1mg/vial, Follistatin 344
Origin: Jiangsu
HS Code: 3001200010
Model NO.: WSPEPHS07
Name: Follistatin 344
Other Name: Follistatin 315, Ace 031
Assay: 99%
Water: 5.43%
Acetic Acid: 6.45%
Trifluoroacetic Acid: 0.08%
Peptide: 88.45%
Payment: Wu, Mg, Tt, Paypal, Wechat
Delivery: 7-15days
Brand: Wide
Trademark: Wide, Follistatin 344
Transport Package: Packed in Glass Bottles
Specification: 1mg/vial, Follistatin 344
Origin: Jiangsu
HS Code: 3001200010
Lab Polypeptide Hormone Peptide Follistatin Fst 344
 
Model: WSPEPHS07
Lab Polypeptide Hormone Peptide Follistatin Fst 344


Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.


Quick Details:
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 95.0%
Formulation: Lyophilized from a concentrated (1mg/ml) solution containing no additives. Solubility: It is recommended to reconstitute the lyophilized Follistatin in sterile 18M -cm H2O not less than 100 G/ml, which can then be further diluted to other aqueous solutions. Stability: Lyophilized Follistatin although stable at room temperature for 3 weeks, should be stored desiccated below -18ºC. Upon reconstitution FST should be stored at 4ºC between 2-7 days and for future use below -18ºC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
 

COA:
Appearance White to off white powder Consistent
Purity(HPLC) ≥98% 99%
Water <6.0% 5.43%
Acetic Acid 3.0-8.0% 6.45%
Trifluoroacetic Acid <0.25% 0.08%
Peptide ≥80% 88.45%
MS Consistent Consistent
 

Description:
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .
 
Lab Polypeptide Hormone Peptide Follistatin Fst 344
Lab Polypeptide Hormone Peptide Follistatin Fst 344



Follistatin and Muscle Growth:
Follistatin works by binding to and inhibiting transforming - (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth.  It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. 
In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.

ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. 

Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the
non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. 

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.
 
Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Lab Polypeptide Hormone Peptide Follistatin Fst 344

 
Peptide List
Melanotan II   10mg/vial ,10vial/box
CJC 1295 2mg/vial ,10vial/box
Frag HG 176 191 2mg/vial ,10vial/box
GHRP-6 5mg/vial ,10vial/box
GHRP-2 5mg/vial ,10vial/box
Thymosin Beta 4 (TB4)(TB-500) 2mg/vial ,10vial/box
Follistatin 344   1mg/vial ,10vial/box
Melanotan I   10mg/vial ,10vial/box
cjc1295 dac 2mg/vial ,10vial/box
Sermorelin 2mg/vial ,10vial/box
Sermorelin 5mg/vial ,10vial/box
PT 141 10mg/vial ,10vial/box
Frag HG 176 191 5mg/vial ,10vial/box
Ipamorelin    2mg/vial ,10vial/box
Ipamorelin    5mg/vial ,10vial/box
MGF                             2mg/vial ,10vial/box
PEG MGF  2mg/vial ,10vial/box
Hexarelin  2mg/vial ,10vial/box
Hexarelin  5mg/vial ,10vial/box
Oxytocin  2mg 2mg/vial ,10vial/box
Lab Polypeptide Hormone Peptide Follistatin Fst 344
 
Model: WSPEPHS07
Lab Polypeptide Hormone Peptide Follistatin Fst 344


Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release.


Quick Details:
Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
Purity: Greater than 95.0%
Formulation: Lyophilized from a concentrated (1mg/ml) solution containing no additives. Solubility: It is recommended to reconstitute the lyophilized Follistatin in sterile 18M -cm H2O not less than 100 G/ml, which can then be further diluted to other aqueous solutions. Stability: Lyophilized Follistatin although stable at room temperature for 3 weeks, should be stored desiccated below -18ºC. Upon reconstitution FST should be stored at 4ºC between 2-7 days and for future use below -18ºC. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
 

COA:
Appearance White to off white powder Consistent
Purity(HPLC) ≥98% 99%
Water <6.0% 5.43%
Acetic Acid 3.0-8.0% 6.45%
Trifluoroacetic Acid <0.25% 0.08%
Peptide ≥80% 88.45%
MS Consistent Consistent
 

Description:
Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .
 
Lab Polypeptide Hormone Peptide Follistatin Fst 344
Lab Polypeptide Hormone Peptide Follistatin Fst 344



Follistatin and Muscle Growth:
Follistatin works by binding to and inhibiting transforming - (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth.  It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow. 
In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.

ACE-031 is intended for research purpose only. ACE-031 should not be used for human consumption, diagnostic, therapeutic procedures, agricultural and veterinary purposes.

ACE-031 is a soluble fusion protein that has been shown to increase muscle mass and strength in research studies. ACE-031 is being studied as a treatment for metabolic diseases, renal neoplasms of childhood, cardiovascular anomalies, age-related muscle loss, and cancer treatment related muscle loss and neuromuscular diseases. ACE-031 is a biologic therapeutic, based on activin receptor type IIB (ActRIIB). The molecule inhibits signaling via the ActRIIB receptor binding and increase muscle mass and strength. ACE-031 is a recombinant fusion protein that is artificially synthesized by fusion of standard antibody and a portion of ActRIIB receptor. The recombinant fusion protein eliminates myostatin and other biomolecules that limit muscle strength or growth.

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries. 

Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the
non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it. 

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.
 
Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Lab Polypeptide Hormone Peptide Follistatin Fst 344

 
Peptide List
Melanotan II   10mg/vial ,10vial/box
CJC 1295 2mg/vial ,10vial/box
Frag HG 176 191 2mg/vial ,10vial/box
GHRP-6 5mg/vial ,10vial/box
GHRP-2 5mg/vial ,10vial/box
Thymosin Beta 4 (TB4)(TB-500) 2mg/vial ,10vial/box
Follistatin 344   1mg/vial ,10vial/box
Melanotan I   10mg/vial ,10vial/box
cjc1295 dac 2mg/vial ,10vial/box
Sermorelin 2mg/vial ,10vial/box
Sermorelin 5mg/vial ,10vial/box
PT 141 10mg/vial ,10vial/box
Frag HG 176 191 5mg/vial ,10vial/box
Ipamorelin    2mg/vial ,10vial/box
Ipamorelin    5mg/vial ,10vial/box
MGF                             2mg/vial ,10vial/box
PEG MGF  2mg/vial ,10vial/box
Hexarelin  2mg/vial ,10vial/box
Hexarelin  5mg/vial ,10vial/box
Oxytocin  2mg 2mg/vial ,10vial/box