Release date: 2017-08-24
The University of Macau research team cooperates in the field, and integrates cutting-edge sciences such as precision medicine, microfluidic chip and image processing into the drug sensitivity screening of cancer cell lines and human primary tumors. Through Australian University's independent research and development, fusion biology and electronics The cutting-edge technology of learning can produce results within 24 hours, providing a practical basis for evidence-based susceptibility testing of precision cancer treatment. The research paper was published in the scientific journal "Scientific Reports" of the Nature Publishing Group.
Under the guidance of Prof. Deng Chuxia, the dean of the Australian University of Health Sciences and the famous biologist, Wang Hengxin completed the experiment and applied the chip to the drug sensitivity screening experiment of cells and human primary tumors. The published paper titled "Drug Screening of Cancer Cell Lines and Human Primary Tumor Cells Using Droplet Microflow". The research mainly tests the sensitivity of cancer cells to different drugs on the microchip developed by the State Key Laboratory of Simulation and Mixed-Signal Very Large Scale Integrated Circuits. The artificial intelligence image processing technology developed by the Institute of Science and Technology is used to observe the drug. Single cell activity in each microdroplet for drug screening and results were obtained within 24 hours.
The microchip used in the experiment has been optimized and improved, only 2.4x2.4 cm, and the manufacturing cost of each chip is low. At present, each microchip can screen up to 9 drugs. After automation, the target screening amount of each chip is 96. a drug. Previous human primary tumor cells could only be used to screen small amounts of drugs, or they needed to be scaled up for large-scale drug screening analysis, and the process would take at least several weeks to produce results.
Source: People's Network
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