Recently, the Ministry of Science and Technology and the State Administration of Traditional Chinese Medicine jointly issued the "Special Plan for TCM Science and Technology Innovation in the 13th Five-Year Plan", proposing to establish a more coordinated, efficient and open TCM scientific and technological innovation system by 2020, and solve a number of restrictions. The key scientific issues in the development of medicine have broken through a number of key core technologies that restrict the development of traditional Chinese medicine, accelerated the modernization and internationalization of traditional Chinese medicine, and established a research model and technical system that is more in line with the inheritance and innovation characteristics of traditional Chinese medicine, and significantly enhanced the technology of traditional Chinese medicine. Innovative ability to further enhance the ability of Chinese medicine to prevent and treat major and difficult diseases and the advantages of Chinese medicine treatment.
The plan is clear, inherit, enrich and develop the theoretical system of Chinese medicine, improve the scientific and technological innovation platform of Chinese medicine, systematically organize, excavate and inherit the academic experience of 100 well-known Chinese medicine experts, and build 1500 kinds of basic ancient Chinese literature digital and resource information bases; 8 to 10 kinds of major diseases and 3 to 5 kinds of difficult diseases, the efficacy level of traditional Chinese medicine, develop a batch of Chinese medicine treatment and disease technology and promote the application; improve the level of Chinese medicine resources and new drug research and development; improve the international standards of Chinese medicine, form no less than 50 Pharmacopoeia standards and 100 industry standards, completed 5 to 10 Chinese patent medicines in developed countries such as Europe and the United States as drug registration, established a number of Chinese medicine research centers and joint laboratories, and strengthen cooperation with countries along the “Belt and Roadâ€; Formulate a number of technical standards for the diagnosis and treatment techniques of ethnic medicines, establish 10 to 15 kinds of clinical diagnosis and treatment programs and guidelines for ethnic medicines, and establish a platform for national medicine resources database, national medicine safety and effectiveness evaluation.
The plan proposes key technologies and innovative methods for development, deepens the inheritance and innovation of TCM theory, enhances the prevention and treatment of major diseases of TCM, develops TCM health service technologies, promotes the protection and value enhancement of TCM resources, and strengthens the development of TCM technology and products. It promotes the standardization and internationalization of Chinese medicine, strengthens the inheritance and innovation of ethnic medicine, builds nine key tasks of the innovation network and support system of Chinese medicine, and links 31 key columns of key technologies and innovative methods, and the inheritance and research of famous Chinese medicine practitioners.
Among them, it is required to strengthen the deep integration of multidisciplinary frontier technologies such as systems biology, big data, artificial intelligence and traditional Chinese medicine. Establish and publish a database of traditional Chinese medicine protection knowledge protection lists, focus on the key issues of holder (protection subject) identification, protection source disclosure, benefit sharing, etc., and promote the establishment of a special protection system for traditional Chinese medicine traditional knowledge under the overall framework of the intellectual property system. Complete a large-scale multi-center clinical study of 6 to 8 Chinese medicines to prevent and cure major diseases, establish 6 to 8 evidence-based guidelines for the prevention and treatment of major diseases of Chinese medicine, and clarify its efficacy mechanism and enter a high-level clinical guide. Focusing on the key technologies of the health status of TCM identification assessment, disease risk prediction and early warning, health intervention, etc., drawing on the achievements of modern life sciences and biomedicine, making full use of information science, big data, Internet and other technologies to improve the treatment of Chinese medicine. The ability and level of illness. Based on the fourth national census pilot work and dynamic monitoring of Chinese medicine resources, the informationization level of Chinese medicine resources and the protection capacity of germplasm resources will be comprehensively improved. Identify potential toxic substances and mechanisms of 200 to 300 commonly used traditional Chinese medicines, establish a database of potential toxic substances, conduct safety evaluation of 50 to 70 commonly used toxic Chinese medicines in the development of new drugs, and develop sensitization of 30 to 50 commonly used traditional Chinese medicine injections. Research on substance screening, identification, control, risk assessment, etc.
In order to ensure the implementation, the plan proposes three measures: overall coordination, diversified investment, improvement of policies, construction system, talent cultivation and discipline integration. It requires the establishment of diversified investment channels for TCM and technology, and guides local governments, enterprises, social institutions and other forces. Increase investment in research funding. We will improve the examination and approval standards and management methods for new Chinese medicines that meet the characteristics and laws of traditional Chinese medicine. Establish a diversified scientific and technological talent evaluation standard oriented to knowledge value, scientific research ability, innovation achievement and application development, improve the incentive mechanism for transforming income distribution of scientific and technological achievements, encourage entrepreneurs of Chinese medicine science and technology, and improve the two-way flow mechanism of scientific research talents.
Attached full text and illustration
Notice of the State Administration of Traditional Chinese Medicine of the Ministry of Science and Technology on Printing and Distributing the Special Plan for the "Thirteenth Five-Year Plan" of Traditional Chinese Medicine Science and Technology Innovation
Guoke Development Agency [2017] No. 146
All provinces, autonomous regions, municipalities directly under the Central Government and the planned separate science and technology departments (committees, bureaus), Chinese medicine administrations, Xinjiang Production and Construction Corps Science and Technology Bureau, Health Bureau, all relevant units:
In accordance with the "Outline of the Thirteenth Five-Year Plan for National Economic and Social Development of the People's Republic of China", the "13th Five-Year National Science and Technology Innovation Plan", and the "Healthy China 2030 Plan", the overall deployment is to accelerate Innovative development of medical science and technology, specially formulated the "13th Five-Year Plan for Traditional Chinese Medicine Science and Technology Innovation". You are now printing, please implement it carefully.
Ministry of Science and Technology
May 12, 2017
"13th Five-Year" Special Plan for Science and Technology Innovation of Traditional Chinese Medicine
Traditional Chinese medicine contains profound scientific connotations and has great potential to lead the future development of life sciences. It is "the treasure of ancient Chinese science" and "the key to opening the treasure house of Chinese civilization". It is a major strategic direction to realize the revitalization and development of Chinese medicine through the scientific and technological innovation to explore the scientific connotation of traditional Chinese medicine and promote the inheritance and innovation of traditional Chinese medicine. According to the "National Innovation Driven Development Strategy Outline", "Health China 2030" Planning Outline, "Chinese Medicine Development Strategy Plan (2016-2030)", "13th Five-Year" National Science and Technology Innovation Plan" and "Ten The “Three-Five†National Social Development Science and Technology Innovation Plan, etc., is designed to accelerate the improvement of TCM scientific and technological innovation capabilities, improve people's health and promote the development of health industry.
I. Situation and needs
(1) The strategic position is more prominent
Since the 18th National Congress of the Communist Party of China, the Party Central Committee with Comrade Xi Jinping as the core has attached great importance to the development of Chinese medicine. General Secretary Xi Jinping has clearly pointed out that it is necessary to "really inherit, develop and make good use of the valuable wealth left by the ancestors of Chinese medicine." . At the National Health and Wellness Conference held in August 2016, General Secretary Xi Jinping emphasized “promoting the innovation of traditional Chinese medicine science and technology†and “working hard to realize the creative transformation and innovative development of the healthy health culture of Chinese medicineâ€. The "National Innovation Driven Development Strategy Outline", "Health China 2030" Planning Outline and "Chinese Medicine Development Strategy Planning Outline (2016-2030)" and other documents all listed TCM science and technology innovation as a development focus. Medical science and technology innovations set clear requirements. The strategic position of TCM science and technology innovation work is more prominent, and it is welcoming the good times of time, location and people.
(2) The technology foundation is more solid
Since the "Twelfth Five-Year Plan", the level of modernization of Chinese medicine has been continuously improved, and breakthroughs in innovation have emerged. The database of traditional Chinese medicine literature and the construction of knowledge base have taken shape, and a series of modern inheritance studies of famous Chinese medicine practitioners have been organized. The original theory of traditional Chinese medicine such as Tibetan elephant theory, acupoint specificity, collateral disease, Chinese medicine medicinal properties, and group distribution Scientific understanding has been further deepened; a number of Chinese medicine diagnosis and treatment equipment have been developed; Chinese medicine has made positive progress in clinical research on prevention and control of cardiovascular and cerebrovascular diseases, diabetes and other major chronic diseases, and major infectious diseases such as influenza A (H1N1), among 16 major diseases. The evidence for the prevention and treatment of medicines has obtained evidence-based evidence; it has broken through a number of endangered and scarce Chinese herbal medicine breeding techniques and key technologies for the cultivation of Chinese herbal medicines. The standardized cultivation techniques of traditional Chinese medicines have been further improved. The quality control level of traditional Chinese medicines has changed from “single†to “wholeâ€; Significant breakthroughs have been made in bottlenecks such as discovery, preparation, and safety evaluation. The technical methods for the development of new Chinese medicines have been continuously improved, and the scientific and technological content of traditional Chinese medicine products has been significantly enhanced. A number of national engineering (technical) research centers and national TCM clinical research bases have been established. Engineering laboratory and enterprise technology center, built 25 The unique Chinese medicine modernization technology industry (planting) base; the pace of internationalization of Chinese medicine has accelerated markedly. Four kinds of Chinese medicines have been approved by the US Food and Drug Administration (FDA) for phase III clinical research, and a batch of proprietary Chinese medicines are being registered in the EU. In the study, a batch of Chinese herbal medicines were included in the US Pharmacopoeia and the European Pharmacopoeia. In particular, in 2015, the Tucson researcher won the Nobel Prize, which fully demonstrated the scientific value of Chinese medicine.
Guided by scientific and technological innovation, the modern Chinese medicine industry is booming. The production system of Chinese herbal medicines is basically established. The number of varieties over 100 million yuan has increased from dozens to 500, and a number of key enterprises of traditional Chinese medicine have been cultivated. The total output value of Chinese medicine industry has been 234 from 1996. 100 million yuan has increased to 786.7 billion yuan in 2015, accounting for a proportion of the total output value of the pharmaceutical industry from 1/5 to 1/3. Chinese medicine products and services have accelerated to the world, and the scale of the Chinese medicine industry has exceeded one trillion yuan. It has played a major role in driving farmers to increase their income, protect the ecological environment, promote regional development, and support the implementation of medical reform.
(3) The space for innovation is broader
At present, new concepts and methods such as systematic complex science, big data, and real-world clinical research are emerging, breaking through the inherent thinking patterns and research models, and promoting the transformation of Chinese medicine research paradigms; biology, electronics, big data, artificial intelligence. The rapid development of advanced technologies has provided strong support for the breakthrough of traditional Chinese medicine research and technology; multi-disciplinary, cross-industry, cooperation at home and abroad has become more extensive, and the depth and breadth of modern science and technology and traditional Chinese medicine have been continuously expanded to accelerate the modernization of traditional Chinese medicine. International development has provided a broader space for innovation.
At the same time, the inheritance crisis and trust crisis of traditional Chinese medicine still exist. The clinical westernization of Chinese medicine and the weakening of the advantages of traditional Chinese medicine are highlighted. The bottlenecks of Chinese herbal medicine resources guarantee and quality control of Chinese medicine are serious, and the international medicine has become a new source of new drug development. Under the trend background, the international competition for Chinese medicine research and development and Chinese medicine standards is becoming increasingly fierce. It is urgent for us to strengthen innovation breakthroughs and accelerate the modernization of Chinese medicine.
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