According to foreign media reports, people can no longer experiment with mice. At present, scientists use a silicon chip for medical testing, which will provide a better way to understand the therapeutic effects of drugs.
Scientists are working on "on-chip organs" to "wrap" important cells, such as lung cells, on a silicon chip, and then simulate the critical functions of the organ. The researchers then tested which drugs would have a significant effect on the lungs. This "on-chip organ" was not large, only a few centimeters long.
In the laboratory, Merck researchers used microchip simulation to design a lung organ with imperfect function and conducted a series of drug experiments to find a new treatment method for asthma. Don Nicholson, head of the company's respiratory medicine research department, said the company's scientists hope that "on-chip organs" will help them better understand the biological characteristics of asthma and identify the most effective drugs. .
American scientists engineer a chip that mimics human lungs
If Merck's medical experiment is effective, drug manufacturers will have a new tool that can save millions of dollars. Christopher Austin, director of the National Center for Advanced Translational Transformation, said the lungs on the chip confirmed the feasibility of the concept. It is reported that Austin's organization is committed to replicating diverse human tissues and organs.
Michael Shuler, head of the Department of Bioengineering at Cornell University in the United States, said: "Ultimately we will build a '10 on-chip organ'."
So far, the technology is still under study, and the drug regulatory authorities are not yet ready to abolish animal experiments altogether, or use current methods to test drug safety and efficacy in clinical patients.
Several drug manufacturers are still reviewing the feasibility of this technology, during which multiple laboratories began simulating the function of the kidneys, liver and other organs.
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