toxicity
1. Toxicity: Intraperitoneal injection of Senna leaves, the LD50 of the mice was 1.141g/kg.
2. Senna can sometimes cause abdominal pain, vomiting, or aggravate the original bowel inflammation (especially in larger amounts).
3. It has been reported that after taking senna, there is facial numbness, dizziness, no feeling or itching in urine and urine, hypoalgesia in the trigeminal nerve distribution area, and urinary retention and malignant blood pressure changes after taking large doses of senna. Wait. The mouse LD50 of Senna leafhopper was 1.414g/kg, equivalent to 36.3g/kg of senna leaf crude drug. This dose was more than 300 times that of clinical senna leaf po treatment.
4. There were 102 patients taking senna leaf, before and after treatment for urine routine, serum creatinine, urea nitrogen, glutamic-pyruvic transaminase, jaundice index and electrocardiogram examination, no significant abnormalities were found.
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