Release date: 2018-02-07
There is never a lack of beauty in life, just the lack of eyes that are good at discovering beauty. In order to infinitely magnify the beauty of biology, researchers rely on microscopes to open a magical space-time tunnel, bringing you a glimpse of the colorful world of creatures. Recently, Cell Magazine has selected a variety of biological "exciting photos" for everyone, so come and enjoy it!
1, magic scissors CRISPR, to overcome the god of disease assistance
The globally popular CRISPR can make extensive revisions to the genomes of cells and even organisms. In the future, it can accurately correct the mutations of genomic target locations to treat hereditary diseases.
Image: Immunohistochemical section staining. The cholangiocarcinoma marker for lung tumors was positive for cytokeratin 19 (Ck19, brown). The image was taken using an optical microscope (10 x lens).
2. Build a mini brain and explore the mysteries of the brain
Imagine a magical picture: When the neural stem cells on the gelatinous matrix slowly begin to differentiate, classify and gather together until they are assembled again into a mini-organ – the brain! The neurons (green) and astrocytes (red) shown in the figure are only part of the "Human on a Chip" project at Griffith Laboratories.
On this bioreactor platform, many different micro-organs are connected together, allowing researchers to study multiple organ interactions and signal exchange processes in an in vitro environment, thereby accelerating the development of innovative disease treatments.
3, thorny glamorous coral, all-encompassing
Corals are mainly composed of individual animals called coral polyps. Like a jellyfish, corals capture food by stimulating cells. But each coral is also a large group. The endosymbiotic algae in the polyps provide nutrients for the corals through photosynthesis. In exchange, corals provide space for them and form structures to ensure that algae are exposed.
Coral reefs made up of tiny animals can scale to a large scale and support the largest number of species per unit area of ​​any other marine environment, making it a valuable ecosystem. Their contribution to the human economy through services such as fisheries, medicine and tourism is about $29.8 billion. To date, 22 species of coral have been classified as endangered species due to pollution, mining and rising ocean temperatures.
4. Radioactive glial cells
GFAP + / Sox2 + radial glial cells in the dentate gyrus of mice. Blue, DAPI; green, GFAP and magenta, Sox2. This picture won the second place in the 2017 MIC Image Competition. It is captured by the Zeiss LSM 880 at 630x magnification (Z-stack).
5, death is like a summer flower
A picture of programmed cell death of SW480 colon cancer cells taken by atomic force microscopy (AFM). After absorbing the gold nanoparticle conjugated photosensitizer, the cancer cells can induce programmed cell death (apoptosis) by laser irradiation, and form pores on the cell membrane and change the film roughness.
6. 'Win-win' in plants
Although competition for space and nutrients by different species is commonplace, many plants also show signs of symbiosis with other species outside the plant kingdom. Some non-vascular plants, such as certain moss species, are supported on the surface of other plants and do not form a parasitic relationship with the host.
Many species in the fungal world can also maintain a symbiotic relationship with plants. Mycorrhizal symbiosis between fungi and plant roots is very common, such as orchids, and this relationship is inseparable from the growth and survival of the host, which provides important nutrients for plants. Fungi also protect host plants from pathogens and carnivores.
7, the main idea behind abdominal pain: intestinal mites
The figure shows the cross section of the locust and won the eighth place in the 2017 MIC Image Competition. It is a picture captured by the Zeiss Axioscan Z.1 with a 200x multiple image scan.
8. Cajal
This is a confocal calcium imaging of Purkinje cells in the cerebellum. The cells are filled with two dyes, a background dye and a calcium-binding dye, both of which are excited by the laser. The painting was named Cahal because its shape is similar to that of the 1906 Nobel Prize in Physiology and Medicine, San Diego Ramon Kahar, for the cerebellum nerve cells.
9, dialogue ChAT, uncover the mystery of flatworm regeneration
The planarian flatworm has significant regenerative capacity for the complex tissue structure of the injury, including the brain and eyes. Each color in the image represents a different level of neurons in the brain and reveals the level of expression of the choline acetyltransferase (ChAT) gene.
However, this image does not show a variety of stem cells that produce a new central nervous system when the flatworm is regenerated. Reddien Laboratories hopes to clarify the cellular molecular basis of biological regeneration by studying flatworms.
10, ocean currents drifting turtles
Ocean currents have a profound impact on all marine life, from passive drifters to highly agile swimmers such as sea turtles. Hatched sea turtles may be carried far away by water, and even adult sea turtles may be taken away during long-distance migration. The journey between the foraging area and the nesting point can be hundreds or even thousands of kilometers. If the long-distance transport is carried out under the current circumstances, the turtle will use the Earth's magnetic field to adjust its direction.
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Source: Spiral/Sub-Fish
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Vitamins are tiny molecules needed to keep the body functioning properly (vitamin B12 is the largest vitamin molecule, with a molecular weight of 1,355). In the article How sunburns and tans are formed, we learned that the body can make its own vitamin D, but usually the vitamin must be supplied through food.
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