Release date: 2014-12-24
Ordinary painkillers, including ibuprofen, may slightly reduce the risk of skin cancer. The researchers reviewed nine previous studies and concluded that the risk of squamous cell skin cancer was reduced by 15% using ibuprofen and naproxen. Squamous cell skin cancer is usually caused by sun exposure.
These painkillers have the potential to be part of a skin cancer prevention strategy. But researchers are not ready to recommend these or other non-steroidal anti-inflammatory drugs (NSAIDs) to prevent skin cancer. Dr. Joshua Zeichner said: Do not rely on taking aspirin or other non-steroidal anti-inflammatory drugs to protect your skin.
The best treatment is primary prevention, such as sunscreen, sun protection and so on. About 22,000 Americans are diagnosed with squamous cell or basal cell skin cancer each year. About 20% of these skin cancers are considered to be squamous cells. Researchers believe that squamous cell skin cancer is usually not dangerous unless they are not treated and metastasized.
Cancer is usually present in parts of the body exposed to the sun, but is often easily removed and therefore rarely causes death. Olsen said: Scientists want to know the ability of certain painkillers to prevent skin cancer, and researchers believe that these drugs may have potential to fight other types of cancer.
The painkillers examined included the effects of aspirin, ibuprofen and naproxen on skin cancer. The study, published in the Journal of Investigative Dermatology, combined the findings of nine existing studies to determine that the use of these drugs (except aspirin) may result in a 15% reduction in the risk of squamous cell skin cancer.
The analysis also suggests that reducing the risk of squamous cell carcinoma is associated with the use of aspirin, Olsen said: but this result was not statistically significant. The association between analgesics and the risk of reducing squamous cell carcinoma is most pronounced in patients with actinic keratosis. However, the above correlation does not prove causality.
Researchers believe that painkillers may reduce the risk of skin cancer by destroying the activity of proteins that contribute to swelling and tumor development. However, she added that more research is needed to determine the appropriate dose before making recommendations. Zeichner said patients want to know if they should take painkillers to prevent skin cancer.
Source: Bio Valley
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