Laboratory-engineered bioengineered blood vessels can replace artificial blood vessels
May 18, 2016 Source: Chinese Industry Information Station
Window._bd_share_config={ "common":{ "bdSnsKey":{ },"bdText":"","bdMini":"2","bdMiniList":false,"bdPic":"","bdStyle":" 0","bdSize":"16"},"share":{ }};with(document)0[(getElementsByTagName('head')[0]||body).appendChild(createElement('script')) .src='http://bdimg.share.baidu.com/static/api/js/share.js?v=89860593.js?cdnversion='+~(-new Date()/36e5)];Scientists have successfully trained human organs in the laboratory and "printed" them out using 3D printing technology. Recently, researchers at Duke University, Yale University, and vascular engineering company Humacyte tested a new type of laboratory cultured vascular implant. After implantation of this bioengineered blood vessel in renal dialysis patients, the results show that it is as safe and reliable as the commonly used artificial blood vessels.
Patients with regular hemodialysis should have a long-term needle, which not only causes damage to the blood vessels, but also faces the problem that the blood vessels cannot be dialyzed after clogging, and it needs to be implanted into blood vessels. However, many patients often encounter artificial vascular infections around the tissue after transplantation, and even have rejection reactions.
The research team did not include living cells in the new blood vessels cultured in the experiment. The researchers found that the blood vessels were implanted in 60 patients with renal failure and found that they performed better than artificial blood vessels. Since this blood vessel does not include any living cells, it is impossible to infect tissue surrounding the blood vessel. The patient did not show rejection after one year of implantation of the blood vessel.
Jeffrey Lawson, a professor of surgery at Duke University and chief medical officer at Humacyte, said: "This bioengineered blood vessel represents a critical step in the development of tissue engineering. Because these blood vessels do not contain living cells, patients have the opportunity to access ready-made bioengineering at any time. Blood vessels, no longer waiting for custom blood vessels for a long time.
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